Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Small Mitral Valve Orifice Area in Mitral Valve Transcatheter Edge-to-Edge Repair: The REPAIR Study.

JACC. Advances·2026
Same author

Killip class at presentation and immediate versus staged multivessel PCI in patients with STEMI.

Scientific reports·2026
Same author

Early outcomes of redo-TAVI with the SAPIEN 3 platform: the prospective, multicentre ReTAVI registry.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·2026
Same author

Impact of concomitant left-sided valve disease on outcomes following tricuspid valve transcatheter edge-to-edge repair: insights from EuroTR.

ESC heart failure·2026
Same author

Impact of Previous Cardiac Surgery on Outcomes After Tricuspid Valve Transcatheter Edge-to-Edge Repair: Insights from EuroTR.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Sex-Specific Outcomes in Patients Undergoing Mitral Valve Transcatheter Edge-to-Edge Repair: The REPAIR Study.

JACC. Advances·2026

Related Experiment Video

Updated: Sep 18, 2025

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

13.5K

How to: Streamlining Pulsed Field Ablation-Based Pulmonary Vein Isolation Using 3D Mapping Without Fluoroscopy.

Yannick Teumer1, Lyuboslav Katov1, Carlo Bothner1

  • 1Ulm University Heart Center, Ulm University, Albert-Einstein-Allee 23, 89081 Ulm, Germany.

Journal of Clinical Medicine
|June 26, 2025
PubMed
Summary

A new variable-loop catheter enables fluoroscopy-free pulmonary vein isolation (PVI) for atrial fibrillation (AF) patients. An optimized workflow significantly reduces procedure time and improves efficiency without compromising safety.

Keywords:
3D mappingatrial fibrillationelectrophysiologyoptimized workflowpulsed field ablationtransesophageal echocardiographyzero fluoroscopy

More Related Videos

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

2.9K
Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

19.8K

Related Experiment Videos

Last Updated: Sep 18, 2025

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

13.5K
Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

2.9K
Robotic Ablation of Atrial Fibrillation
11:21

Robotic Ablation of Atrial Fibrillation

Published on: May 29, 2015

19.8K

Area of Science:

  • Electrophysiology
  • Medical Devices
  • Cardiology

Background:

  • Pulsed field ablation (PFA) is effective for pulmonary vein isolation (PVI) in atrial fibrillation (AF).
  • Traditional PFA often requires fluoroscopy, posing health risks due to X-ray exposure.
  • First-generation PFA catheters lack 3D mapping integration, necessitating fluoroscopic guidance.

Purpose of the Study:

  • To evaluate and optimize a zero-fluoroscopy workflow for PVI using a novel variable-loop PFA catheter (VLC).
  • To assess the safety and efficiency of a fully 3D-integrated VLC for PVI without fluoroscopy.

Main Methods:

  • Comparison of two zero-fluoroscopy workflows: conventional (pre-ablation mapping) and optimized ('mapping-on-the-fly').
  • The 'mapping-on-the-fly' approach integrates real-time mapping and ablation sequentially for each pulmonary vein.
  • Utilized a new variable-loop PFA catheter with integrated 3D mapping capabilities.

Main Results:

  • Successfully treated 41 pulmonary veins in 10 AF patients without fluoroscopy.
  • The 'mapping-on-the-fly' workflow significantly reduced procedural time (median 68 vs. 144 min) and left atrial dwell time (46 vs. 107 min).
  • No fluoroscopy-related complications were observed during the procedures.

Conclusions:

  • Pulmonary vein isolation (PVI) using the 3D-integrated VLC is safe and efficient without fluoroscopy.
  • The optimized 'mapping-on-the-fly' workflow enhances procedural efficiency for zero-fluoroscopy PVI.
  • This approach minimizes radiation exposure for patients and staff during AF treatment.