Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Halogens03:01

Halogens

19.4K
Group 17 elements, known as halogens, are nonmetals. At room temperature, fluorine and chlorine are gases, bromine is a liquid, and iodine a solid. Astatine is a highly unstable radioactive element, so currently, most of its properties are unknown due to its short half-life. Tennessine is a synthetic element also predicted to be in this group. 
19.4K
Hybridization of Atomic Orbitals II03:35

Hybridization of Atomic Orbitals II

33.9K
sp3d and sp3d 2 Hybridization
33.9K
Exceptions to the Octet Rule02:55

Exceptions to the Octet Rule

29.9K
Many covalent molecules have central atoms that do not have eight electrons in their Lewis structures. These molecules fall into three categories:
29.9K
Formal Charges02:42

Formal Charges

34.0K
In some cases, there are seemingly more than one valid Lewis structures for molecules and polyatomic ions. The concept of formal charges can be used to help predict the most appropriate Lewis structure when more than one reasonable structure exists.
34.0K
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

22.4K
In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
22.4K
Alkyl Halides02:45

Alkyl Halides

17.5K
Structural Properties
Alkyl halides are halogen-substituted alkanes wherein one or more hydrogen atoms of an alkane is replaced by a halogen atom such as fluorine, chlorine, bromine, or iodine. The carbon atom in an alkyl halide is bonded to the halogen atom, which is sp3-hybridized and exhibits a tetrahedral shape.
Unlike alkyl halides, compounds in which a halogen atom is bonded to an sp2 -hybridized carbon atom of a carbon-carbon double bond (C=C) are called vinyl halides. Whereas aryl...
17.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photoinduced Enhancement of Chemical Shift Sensitivity to Local Vibrations.

Journal of the American Chemical Society·2026
Same author

Matrix tolerance, probe orientation, and antifouling interfaces in graphene biosensors.

Biosensors & bioelectronics·2026
Same author

Stabilising high-spin, high-valent transition-metal-oxo species in cucurbit[5]uril: correlating structure, spin state, and reactivity.

Physical chemistry chemical physics : PCCP·2026
Same author

Mn(III)-O-Ce(IV) as a Surrogate for Highly Reactive Non-Heme Mn(IV)═O Species Supported by Benzimidazole-Based Ligand.

Inorganic chemistry·2026
Same author

Computational insights into the encapsulation of a Dy(III) bis(amide)-alkene single-ion magnet within porous frameworks.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Quantifying Magnetic Anisotropy of Ferroelectric Fe(II) Square-Pyramidal Systems Using Torque Magnetometry.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Related Experiment Video

Updated: Sep 18, 2025

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
12:27

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes

Published on: September 8, 2013

11.0K

Formal Cu(III) Species Featuring Dangling Hypochlorite.

Raju Eerlapally1, Purva Dua2, Divya Lakshmi Hareendran1

  • 1Southern Laboratories, Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India.

Inorganic Chemistry
|June 26, 2025
PubMed
Summary

Researchers developed a novel copper complex featuring hypochlorite bound to the secondary coordination sphere, mimicking natural halogenating enzymes. This unique complex demonstrates reactivity in hydrogen atom abstraction reactions.

More Related Videos

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.2K
Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV
10:42

Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV

Published on: December 29, 2016

10.8K

Related Experiment Videos

Last Updated: Sep 18, 2025

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
12:27

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes

Published on: September 8, 2013

11.0K
From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.2K
Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV
10:42

Combining Solid-state and Solution-based Techniques: Synthesis and Reactivity of ChalcogenidoplumbatesII or IV

Published on: December 29, 2016

10.8K

Area of Science:

  • Bioinorganic Chemistry
  • Organometallic Chemistry
  • Enzyme Mimicry

Background:

  • Natural halogenation of organic compounds involves halogenases and haloperoxidases utilizing metal-hypochlorite or enzyme-bound hypochlorous acid (HOCl).
  • These enzymes play crucial roles in biological processes, inspiring the design of synthetic mimics.

Purpose of the Study:

  • To characterize a novel formal copper(III) complex with a hypochlorite ligand in the secondary coordination sphere.
  • To investigate the binding mode and electronic structure of the hypochlorite within the complex.
  • To explore the reactivity of the designed complex in hydrogen atom abstraction reactions.

Main Methods:

  • Synthesis and characterization of the formal Cu(III) complex using UV/Vis absorption, Electron Paramagnetic Resonance (EPR), X-ray Absorption Spectroscopy (XAS), and resonance Raman spectroscopy.
  • Computational analysis to determine the energetically favored ground state structure and bonding interactions.
  • Reactivity studies involving hydrogen atom abstraction from substituted phenol derivatives.

Main Results:

  • Spectroscopic data confirmed the presence of a formal Cu(III) complex with hypochlorite.
  • Resonance Raman and computational studies indicated that hypochlorite is hydrogen-bonded to the ligand's amine groups (secondary coordination sphere) rather than directly coordinating to the copper center.
  • The complex exhibited reactivity in hydrogen atom abstraction from phenol derivatives.

Conclusions:

  • A unique copper-hypochlorite complex was synthesized and characterized, featuring non-coordinating hypochlorite bound via hydrogen bonding.
  • This represents a novel example of hypochlorite interaction within the secondary coordination sphere of a metal complex.
  • The complex serves as a functional mimic of certain enzymatic halogenation pathways and demonstrates potential for synthetic applications.