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Evaluation of Biodegradable Temporizing Matrix for Functional and Aesthetic Outcomes in Hand Soft-tissue Defect: A
Usama Farghaly Omar1, Vinnie Eleanor Lim2, Shirong Huang1
1From the Hand and Reconstructive Microsurgery Service, Orthopaedic Surgery Department, Khoo Teck Puat Hospital, Singapore.
Background:
Hand soft-tissue defects compromise both function and aesthetics, significantly impacting quality of life. Traditional reconstructive techniques frequently lead to complications, such as donor-site morbidity and suboptimal aesthetic outcomes. The NovoSorb biodegradable temporizing matrix (BTM) may address these challenges by promoting tissue ingrowth. This study evaluates BTM's effectiveness in managing hand soft-tissue defects.
Methods:
A retrospective cohort study was conducted on 67 patients who underwent BTM placement for hand soft-tissue defects from July 2020 to May 2024. Data were collected on patients' demographics, wound size, cause of injury, time to tissue integration, postoperative complications, and clinical outcomes. Functional outcomes were assessed using range of motion and grip strength, whereas aesthetic outcomes were evaluated using the Patient and Observer Scar Assessment Scale (POSAS). Descriptive and correlational analyses explored the relationship between wound size, return to work, and outcomes.
Results:
Among the 67 patients (58 men, 9 women; mean age 43.3 y), 97% achieved successful BTM integration, with only 2 cases of failure due to poor vascularity. The mean range of motion for metacarpophalangeal joints was 76.17 degrees, and grip strength averaged 21.3 kg. Functional outcomes, based on the Finger Injury Outcome Score, were good to excellent in 58.2% of cases. Aesthetic outcomes were generally favorable, with a mean POSAS observer score of 3.58. The correlation between wound size and return to work was weak (r = 0.132).
Conclusions:
NovoSorb BTM appears to be a promising alternative for managing complex hand injuries, providing both functional and aesthetic benefits with minimal complications.
