Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Framing Effects

Framing Effects

Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...

Association Areas of the Cortex

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A peroxisomal metabolic route from benzoyl-CoA to benzyl alcohol for phenylalanine-derived salicylic acid biosynthesis in rice.

Molecular plant·2026

Same author

Asthma increased the risk of atrial fibrillation: insights from clinical association to genetic and molecular evidence.

BMC pulmonary medicine·2026

Same author

Establishment and Parameter Calibration of a Discrete Element Model for Shanghai Bok Choy Plug Seedling.

Plants (Basel, Switzerland)·2026

Same author

Rational design, molecular characterization and dissociation mechanisms of PROTACs targeting hFAAH.

Physical chemistry chemical physics : PCCP·2026

Same author

A longitudinal study on the effect of aerobic exercise intervention on working memory of college students with internet addiction.

Scientific reports·2026

Same author

An MRI-based radiomics model for precision subtyping of hereditary spastic paraplegia: discriminating SPG4 from SPG5.

Neuroradiology·2026

Same journal

Analysis of acute stroke-like lesions in MELAS: Distribution, potential boundaries and spreading pattern.

Neuroimage. Reports·2026

Same journal

Deep learning-based identification of causative genes in lissencephaly using 3D-MRI volumetric datasets.

Neuroimage. Reports·2026

Same journal

Identification of abnormal neural language networks by reading "brainprints" in patients with brain tumors.

Neuroimage. Reports·2026

Same journal

Ambiguity tolerance and resting-state functional connectivity: A preregistered conceptual replication in a Japanese sample.

Neuroimage. Reports·2026

Same journal

Decreased variability of small-world propensity during non-response tasks in schizophrenia.

Neuroimage. Reports·2026

Same journal

The damaged connectome: Mechanisms and consequences of brain network reorganization following neurotrauma.

Neuroimage. Reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 18, 2025

Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention

Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention

Published on: November 16, 2017

Domain-specific neural substrates underlie the framing effect.

Sai Sun^1,2, Jianping Hu³, Rongjun Yu⁴

¹Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, 980-8578, Japan.

Neuroimage. Reports

|June 26, 2025

Summary

This summary is machine-generated.

The framing effect influences decisions similarly in gain and loss domains. However, the brain uses different regions: the amygdala for gains and the striatum for losses, revealing domain-specific neural mechanisms in decision-making.

Keywords:

Amygdala Domain-specific Framing effect Putamen fMRI

More Related Videos

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

Related Experiment Videos

Last Updated: Sep 18, 2025

Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention

Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention

Published on: November 16, 2017

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

Area of Science:

Neuroscience
Decision Science
Cognitive Psychology

Background:

The framing effect, where decision-making is biased by how options are presented, is well-documented.
Previous research linked the amygdala to the framing effect primarily in the gain domain.
Understanding the framing effect in the loss domain is crucial for survival and evolutionary contexts.

Purpose of the Study:

To investigate and compare the neural mechanisms of the framing effect in both gain and loss domains.
To replicate previous findings on the framing effect in the gain domain.
To identify domain-specific neural substrates underlying decision-making biases.

Main Methods:

Replicated gain domain framing effect findings using a similar experimental design.
Employed functional magnetic resonance imaging (fMRI) to examine brain activity and connectivity.
Compared behavioral and neural responses across gain and loss framing conditions.

Main Results:

Behaviorally, participants exhibited comparable framing effects in both gain and loss domains, indicating frame-indiscriminate bias.
Neuronal analysis revealed the amygdala's specific role in the gain domain framing effect.
The striatum was identified as the key region for the framing effect in the loss domain, with distinct connectivity patterns.

Conclusions:

Decision-making biases due to framing effects show domain-specific neural underpinnings.
The amygdala and striatum play distinct roles in processing framed choices in gain versus loss contexts.
Highlights the importance of considering gain/loss domains and the cortical-striatal-limbic network in decision-making research.