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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Patients' Perspectives on Breast Reconstruction in Sub-Saharan Africa
Natalie M Guzman1,2, Brigit D Baglien3, Eden S Kassa4
1Department of Learning Health Sciences, University of Michigan, Ann Arbor.
JAMA Network Open
|June 26, 2025
Summary
Breast reconstruction perceptions in sub-Saharan Africa are complex, influenced by identity, age, and beliefs. Understanding these views is key to improving breast cancer care and quality of life for women undergoing mastectomy.
Area of Science:
- Oncology
- Global Health
- Qualitative Research
Background:
- Mastectomy hesitation in sub-Saharan Africa leads to late diagnosis and high mortality.
- Mastectomy significantly reduces quality of life for women in the region.
- Breast reconstruction may enhance treatment acceptance and quality of life, but its perceptions are understudied in Africa.
Purpose of the Study:
- To explore sociocultural perspectives, attitudes, and perceptions regarding breast reconstruction among female breast cancer patients in sub-Saharan Africa.
Main Methods:
- Qualitative study conducted in Ghana and Ethiopia (December 2023 - February 2024).
- Semi-structured interviews with 46 breast cancer patients.
- Content analysis of interview data.
Main Results:
- Perceptions balanced the role of breasts in self-identity versus function.
- Attitudes varied by life stage, with younger, dating women more receptive to reconstruction.
- Opinions ranged from viewing reconstruction as natural to conflicting with divine will.
Conclusions:
- Sociocultural factors create complex perspectives on breast reconstruction in sub-Saharan African women.
- Findings can inform tailored interventions for patient-centered counseling and improved quality of life.
- Addressing these perceptions is crucial for holistic breast cancer care in the region.

