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Related Experiment Video

Updated: Jun 19, 2026

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Screening for developmental delay at 18 months using the Infant Toddler Checklist: A validation study.

Cornelia M Borkhoff1,2, Haris Imsirovic3, Imaan Bayoumi3,4

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Summary

The Infant Toddler Checklist (ITC) shows high specificity for detecting developmental concerns in toddlers. While it has low sensitivity, a positive ITC score predicts increased healthcare use, including neurodevelopmental consultations.

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Area of Science:

  • Pediatric Health
  • Developmental Pediatrics
  • Health Services Research

Background:

  • Early detection of developmental concerns is crucial for timely intervention.
  • The Infant Toddler Checklist (ITC) is a potential tool for screening at the 18-month well-child visit.
  • Understanding the predictive validity and healthcare utilization associated with positive ITC screening is important.

Purpose of the Study:

  • To examine the predictive validity of the Infant Toddler Checklist (ITC).
  • To assess the association between positive ITC screening and subsequent healthcare utilization (HCU).

Main Methods:

  • Prospective cohort study of 1460 children at their 18-month primary care visit.
  • Parents completed the ITC; health administrative databases tracked healthcare utilization.
  • Neurodevelopmental consultation was the primary outcome measure.

Main Results:

  • 11% of children screened ITC positive; 2.6% received a neurodevelopmental consultation by age 8.
  • The ITC demonstrated 40% sensitivity and 90% specificity for detecting neurodevelopmental consultation.
  • A positive ITC was significantly associated with increased rates of 6 of 7 HCU types, including neurodevelopmental consultation (aRR 2.78).

Conclusions:

  • The ITC exhibits high specificity and a low false positive rate, minimizing unnecessary anxiety and resource use for most children.
  • The low sensitivity of the ITC underscores the necessity of continued developmental surveillance.
  • Findings suggest the ITC can be a valuable screening tool when complemented by ongoing developmental monitoring.