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Internet-based acceptance and commitment therapy for bipolar disorder: A randomized controlled pilot trial.

Gulimire Isak1, Manqi Cai1, Zhihui Zhang1

  • 1Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan 430079, PR China; Key Laboratory of Human Development and Mental Health of Hubei Province, School of Psychology, Central China Normal University, Wuhan 430079, PR China.

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Summary
This summary is machine-generated.

A brief internet-based Acceptance and Commitment Therapy (iACT) program shows feasibility for bipolar disorder (BD). This digital intervention improved psychological flexibility and reduced manic symptoms, supporting further research.

Keywords:
Acceptance and commitment therapyBipolar disorderCognitive FusionDepressionInternet-based interventionManiaPilot trialPsychological Flexibility

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Area of Science:

  • Psychiatry
  • Digital Therapeutics
  • Mental Health Interventions

Background:

  • Bipolar disorder (BD) management often requires scalable and accessible interventions.
  • Internet-based Acceptance and Commitment Therapy (iACT) presents a potential solution, but its feasibility and efficacy in BD are not well-established.

Purpose of the Study:

  • To evaluate the acceptability, feasibility, and preliminary efficacy of a 7-day self-guided iACT program for adults with BD.
  • To assess recruitment, retention, adherence, and clinical outcomes compared to a digital psychoeducation control group.

Main Methods:

  • Pilot randomized controlled trial with 60 clinically stable adults with BD.
  • Participants were randomized to iACT (n=30) or digital psychoeducation (n=30).
  • Outcomes included psychological flexibility, cognitive fusion, social functioning, and manic/depressive symptoms.

Main Results:

  • High recruitment (85.7%) and 100% retention were achieved.
  • iACT group showed significant improvements in psychological flexibility, reduced cognitive fusion, better social functioning, and lower manic symptoms (Cohen's d = -0.28 to -0.59).
  • Adherence to the iACT program was high (93.3% completed ≥5 modules).

Conclusions:

  • A brief, self-guided iACT program is feasible and acceptable for individuals with BD.
  • Preliminary efficacy suggests iACT can improve key psychological and clinical outcomes in BD.
  • Results warrant a definitive randomized controlled trial to confirm clinical effectiveness.