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Predicting enamel depth distribution of maxillary teeth based on intraoral scanning: A machine learning study
Du Chen1,2, Xiang He3, Qijing Li1,2
1State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Journal of Prosthodontic Research
|June 26, 2025
Summary
This study developed a machine learning (ML) framework using intraoral scanning (IOS) images to non-invasively predict enamel depth distribution (EDD). The ML model demonstrated accurate EDD predictions, offering a radiation-free alternative for dental applications.
Area of Science:
- Biomedical Engineering
- Dental Materials Science
- Artificial Intelligence in Healthcare
Background:
- Accurate enamel depth distribution (EDD) is crucial for dental procedures like preoperative design, restorative previews, and monitoring enamel wear.
- Current methods for obtaining EDD lack non-invasive and efficient capabilities.
- Intraoral scanning (IOS) offers a promising non-invasive imaging modality for dental diagnostics.
Purpose of the Study:
- To develop a machine learning (ML) framework for non-invasive and radiation-free prediction of enamel depth distribution (EDD).
- To utilize intraoral scanning (IOS) images as input for the ML model to estimate EDD.
- To provide a novel method for preoperative design, aesthetic preview, and enamel wear monitoring.
Main Methods:
- A machine learning framework was developed using cone-beam computed tomography (CBCT) and IOS images from 200 volunteers.
- Five-dimensional features were extracted from labial enamel surfaces and used to train an eXtreme gradient boosting (XGB) model.
- The model's accuracy was evaluated using R-squared and mean absolute error (MAE), with predictions compared against CBCT-derived ground truths.
Main Results:
- The XGB model achieved high training accuracy with an average R-squared of 0.926 and MAE of 0.080.
- Independent validation demonstrated robust EDD prediction capabilities with no significant deviation from ground truths.
- Low prediction errors (Frobenius norm: 12.566-18.312) were observed, indicating reliable performance despite minor IOS noise.
Conclusions:
- Preliminary validation confirms the efficacy of an IOS-based ML model for high-quality EDD prediction.
- This non-invasive, radiation-free approach shows potential for improving dental diagnostics and treatment planning.
- Further research can explore broader clinical applications of this ML framework in dentistry.
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