Related Experiment Video
Updated: Sep 18, 2025
08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.5K
Surgical site infections: a comprehensive review
Ahmad Reza Rezaei1,2, Damian Zienkiewicz1, Amir Reza Rezaei1
1Medical University of Bialystok, Białystok, Poland.
Journal of Trauma and Injury
|June 26, 2025
Summary
Surgical site infections (SSIs) are a significant global health issue. Implementing evidence-based prevention strategies, including aseptic techniques and antibiotic prophylaxis, is crucial for reducing infection rates and improving patient outcomes.
Area of Science:
- Infectious Diseases
- Public Health
- Surgical Care
Background:
- Surgical site infections (SSIs) pose a substantial global health burden, increasing patient morbidity, mortality, and healthcare expenditures.
- Key concerns include rising antibiotic resistance and instrument contamination, particularly in resource-limited environments.
Purpose of the Study:
- To provide a comprehensive review of the epidemiology, risk factors, microbiology, treatment, and prevention of SSIs.
- To synthesize contemporary research and evidence-based practice protocols for SSI management.
Main Methods:
- An extensive literature review was conducted using PubMed, Embase, and Cochrane Library.
- Inclusion criteria focused on peer-reviewed articles and guidelines from major surgical and public health organizations.
- The PECO framework guided the review process.
Main Results:
- Trauma patients, especially those with open fractures or undergoing emergency surgery, face elevated SSI risks.
- Antibiotic resistance and surgical instrument contamination are critical global challenges.
- Effective prevention hinges on preoperative interventions, aseptic techniques, and appropriate antibiotic prophylaxis.
Conclusions:
- Reducing SSI incidence requires a multifaceted approach encompassing robust preventive strategies.
- Adherence to evidence-based protocols is essential for mitigating the impact of SSIs.
- Improved patient outcomes are directly linked to effective SSI prevention and management.
Related Concept Videos
01:22Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
01:21Inflammatory Bowel Disease V: Surgical Management
224
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
224
01:25Urinary Tract Calculi VI: Surgical Management
37
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
37
01:25Peptic Ulcer Disease V: Surgical Management and Nursing Care
420
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
420
01:28Asepsis
2.4K
The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
2.4K
01:26Factors Affecting the Risk of Infection
12.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.3K