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Artificial Intelligence in Pediatric Orthopedics: A Comprehensive Review
Andrea Vescio1,2, Gianluca Testa3, Marco Sapienza3
1Department of Life Science, Health, and Health Professions, Link Campus University, 00165 Rome, Italy.
Medicina (Kaunas, Lithuania)
|June 27, 2025
Summary
Artificial intelligence (AI) shows promise in pediatric orthopedics for diagnosis and treatment planning. However, current studies need more validation and standardized data to ensure safe clinical use.
Area of Science:
- Orthopedic Surgery
- Medical Imaging
- Artificial Intelligence
Background:
- Artificial intelligence (AI), including machine learning (ML) and deep learning (DL), is increasingly used in medicine.
- AI adoption in pediatric orthopedics is growing but lacks comprehensive review.
- This study reviews current AI applications in pediatric orthopedics.
Purpose of the Study:
- To systematically review the latest evidence on AI applications in pediatric orthopedics.
- To identify AI's role in diagnosing and managing pediatric orthopedic conditions.
- To highlight current limitations and future directions for AI in this field.
Main Methods:
- Literature search of PubMed and Web of Science databases up to March 2024.
- Selection of studies on AI in pediatric spinal deformities, hip disorders, trauma, bone age assessment, and limb discrepancies.
- Categorization of studies by AI application, models, datasets, and outcomes.
Main Results:
- AI models achieve high accuracy in spinal deformity classification (e.g., >90% with SVM, CNN).
- Deep learning excels in diagnosing hip dysplasia and detecting pediatric fractures (e.g., YOLO, ResNet).
- AI matches or surpasses traditional methods for bone age estimation, but studies often lack external validation and use small datasets.
Conclusions:
- AI has significant potential to improve diagnostic accuracy and decision-making in pediatric orthopedics.
- Current research faces limitations due to inconsistent methodologies and lack of standardized validation.
- Future research should prioritize multicenter data, prospective validation, and interdisciplinary collaboration for safe clinical integration.

