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Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
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Enhancing the Drug Release and Physicochemical Properties of Rivaroxaban via Cyclodextrin Complexation: A

Cristina Solomon1, Valentina Anuța2, Iulian Sarbu3

  • 1Faculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia St., 020956 Bucharest, Romania.

Pharmaceuticals (Basel, Switzerland)
|June 27, 2025
PubMed
Summary

This study enhanced rivaroxaban solubility using cyclodextrin inclusion complexes and lyophilization. The resulting formulations showed improved stability and dissolution, comparable to commercial Xarelto.

Keywords:
drug releasehydroxypropyl-β-cyclodextrinmethyl-β-cyclodextrinpharmaceutical formulationrivaroxabansolubility enhancementβ-cyclodextrin

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