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Central obesity and post-stroke depression: Implications for stroke recovery
Eguono Deborah Akpoveta1, Uchenna Esther Okpete2, Haewon Byeon3
1Department of Community Medicine, Federal Medical Centre, Asaba 322022, Delta, Nigeria.
World Journal of Psychiatry
|June 27, 2025
Summary
Central obesity, measured by weight-to-waist index (WWI), is increasingly linked to post-stroke depression (PSD). WWI may offer a better indicator than BMI for identifying at-risk stroke survivors for targeted interventions.
Area of Science:
- Neurology
- Psychiatry
- Metabolic Health
Background:
- Post-stroke depression (PSD) is a common complication impacting stroke survivor recovery.
- Traditional obesity metrics like BMI may not fully reflect risks associated with visceral fat.
- Central obesity, indicated by weight-to-waist index (WWI), is emerging as a key factor in PSD.
Discussion:
- WWI offers a more precise measure of metabolic and inflammatory factors contributing to post-stroke mental health issues.
- Integrating WWI into stroke rehabilitation assessments can aid in early risk identification.
- This approach may improve the effectiveness of interventions for PSD.
Key Insights:
- Weight-to-waist index (WWI) shows promise as a predictor for post-stroke depression (PSD).
- WWI may be superior to BMI in assessing neuropsychiatric risks related to central obesity.
- Routine WWI assessment could enhance PSD management strategies.
Outlook:
- Further research is required to establish standardized WWI cutoff values for PSD risk.
- Investigating WWI's role in metabolic and inflammatory pathways is crucial.
- Identifying therapeutic targets for PSD prevention based on WWI is a future direction.
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