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[Fever in renal cell carcinoma]
Gan No Rinsho. Japan Journal of Cancer Clinics
|August 1, 1985
Summary
Fever is a common symptom in renal cell carcinoma patients, often indicating more severe disease. This symptom is linked to poorer prognosis and other systemic issues in these patients.
Area of Science:
- Oncology
- Nephrology
- Internal Medicine
Context:
- Renal cell carcinoma (RCC) is a significant health concern.
- Understanding symptom presentation is crucial for diagnosis and management.
- Fever's role in RCC requires further elucidation.
Purpose:
- To investigate the frequency and clinical significance of fever in renal cell carcinoma patients.
- To identify associated symptoms and histological features in patients with fever.
- To determine the impact of fever on prognosis in renal cell carcinoma.
Summary:
- Fever occurred in 37.8% of 172 renal cell carcinoma patients, ranking third in frequency after hematuria and renal mass.
- Fever was associated with palpable renal mass, malaise, anorexia, weight loss, elevated ESR, liver dysfunction, and increased alpha 2-globulin.
- High-grade tumors and poorer prognosis were significantly more common in patients who developed fever.
Impact:
- Highlights fever as a potential indicator of advanced or aggressive renal cell carcinoma.
- Suggests fever presence warrants comprehensive evaluation for systemic involvement and prognostic assessment.
- Informs clinical practice regarding symptom monitoring and patient stratification in renal cell carcinoma.