[Fever in renal cell carcinoma]

Fever developed in 65 (37.8%) out of 172 patients with renal cell carcinoma, being the third most frequent symptom following hematuria and renal mass. Patients who developed fever were associated with symptoms such as palpable renal mass, general malaise anorexia, weight loss, acceleration in ESR, liver dysfunctions and an increase in alpha 2-globulin significantly more frequently than those who did not. Histologically also, high graded cases were more common with a significant. Moreover, the prognosis was significantly more poor.