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Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma: Pathogenesis and Management01:20

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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Related Experiment Video

Updated: Sep 17, 2025

Conducting Respiratory Oscillometry in an Outpatient Setting
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An update on oscillometry in asthma.

Francesco Menzella1, Rory Chan2, Carlo Lombardi3

  • 1Pulmonology Unit, S. Valentino Hospital, Montebelluna (TV), AULSS2 Marca Trevigiana, Treviso, Italy.

Expert Review of Respiratory Medicine
|June 27, 2025
PubMed
Summary
This summary is machine-generated.

Airway oscillometry (AO) is crucial for detecting small airways dysfunction (SAD) in asthma, even with normal spirometry. This method aids in early diagnosis and improved asthma management, transitioning AO into a clinical tool.

Keywords:
FOTIOSSevere asthmabiologicsoscillometrysmall airways dysfunctionspirometry

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Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Clinical Diagnostics

Background:

  • Suboptimal asthma control affects many patients despite treatment advancements.
  • Small airways dysfunction (SAD) is a key factor in airflow limitation and asthma exacerbations.
  • Airway oscillometry (AO) is vital for assessing SAD.

Purpose of the Study:

  • To review the literature on the role of AO in asthma management.
  • To highlight AO's utility in detecting SAD, especially when spirometry is normal.
  • To discuss the evolution of AO from a research to a clinical tool.

Main Methods:

  • Literature review of English-language studies up to June 2025.
  • Analysis of the role of AO in quantifying SAD.
  • Examination of correlations between AO, imaging, and biomarkers.

Main Results:

  • AO is effective in quantifying SAD.
  • Strong correlations exist between AO, advanced imaging, and type 2 biomarkers.
  • AO is recommended for early SAD detection, independent of spirometry results.

Conclusions:

  • AO is an essential tool for early SAD detection in asthma.
  • The use of AO in diagnosing severe SAD signifies its clinical utility.
  • AO enhances asthma management by identifying a critical site of airflow limitation.