Related Experiment Video
Updated: Sep 17, 2025

10:19
Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing
Published on: February 13, 2016
11.5K
Membrane Microfiltration by Recirculating the Surface Flow of a Suspension Droplet
Uddipta Singha1, Prasanna S Gandhi1
1Suman Mashruwala Advanced Microengineering Laboratory, Department of Mechanical Engineering, Indian Institute of Technology Bombay, Mumbai 400076, India.
Langmuir : the ACS Journal of Surfaces and Colloids
|June 27, 2025
Summary
This study introduces a novel Hele-Shaw flow method for efficient membrane filtration of particle suspensions. The technique enhances filter efficiency by using shear-induced particle migration to prevent membrane clogging.
Area of Science:
- Fluid Dynamics
- Membrane Science
- Microfluidics
Background:
- Membrane filtration is crucial for separating particles from liquids.
- Traditional methods can suffer from membrane fouling and reduced efficiency.
- Controlling particle behavior within the suspension is key to improving filtration.
Purpose of the Study:
- To develop and validate a novel Hele-Shaw flow-based method for enhanced membrane filtration.
- To investigate the role of shear-induced particle migration in improving filter performance.
- To optimize experimental parameters for maximizing filtrate yield and efficiency.
Main Methods:
- Utilized a sphere-on-flat, lifted Hele-Shaw cell (SoF-LHSC) with oscillatory motion.
- Employed shadowgraphy to visualize flow dynamics and particle migration.
- Conducted parametric analysis to determine optimal operating conditions.
- Quantified filtration performance using shear diffusivity and cake resistance.
Main Results:
- Demonstrated that shear-induced particle migration effectively drives particles away from the membrane, preventing clogging.
- Identified an optimal plate velocity for filtration, beyond which efficiency diminishes.
- Achieved a filtrate yield of 47.98 ± 13.49% from a 30 μL suspension of 7 μm beads using a 0.4 μm membrane in 5 minutes.
- Showed that increased particle size and reduced membrane resistance enhance filter flux.
Conclusions:
- The SoF-LHSC method offers a promising approach for efficient membrane filtration of particulate suspensions.
- Shear-induced particle migration is a critical factor in enhancing filter performance and longevity.
- The method has potential applications in sample concentration, impurity removal, and filtrate extraction.

