Partial Middle Turbinate Resection Versus Preservation on Olfactory Function: A Systematic Review and Meta-Analysis.

Area of Science:

• Otolaryngology
• Rhinology
• Olfactory Neuroscience

Background:

• The middle turbinate (MT) plays a role in olfactory function, but its surgical management remains debated.
• Partial resection versus preservation of the MT during nasal surgery is a key consideration for olfactory outcomes.

Purpose of the Study:

• To compare the olfactory outcomes between partial middle turbinate resection (MTR) and middle turbinate preservation (MTP).

Main Methods:

• A systematic literature search was conducted across major databases (Cochrane Library, Embase, PubMed, Scopus, Web of Science) up to February 10, 2024.
• Seven eligible studies comparing olfactory outcomes between partial MTR and MTP were included.
• A random-effects model was used to calculate standardized mean differences (SMD) for olfactory function scores, with subgroup analyses performed.

Main Results:

• Overall, no significant difference in olfaction was found between partial MTR and MTP (SMD, 0.140; P = .359).
• Subgroup analysis revealed a significant benefit of partial MTR in objective olfactory tests (SMD, 0.370; P < .001).
• No significant differences were observed in subjective tests, functional endoscopic sinus surgery, endoscopic endonasal approach for skull base surgery, or follow-up durations exceeding 6 months.

Conclusions:

• Partial middle turbinate resection (MTR) does not lead to olfactory dysfunction when compared to middle turbinate preservation (MTP).
• Given the potential benefits observed in objective testing, partial MTR may be a favorable surgical approach in clinical practice.