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Updated: Sep 17, 2025
Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
Published on: May 3, 2017
Dorsal Root Ganglion Stimulation as a Treatment for Chronic Refractory Groin Pain: A Case Series
Madhur Batra1, Christopher J Mallard2
1University of Kentucky, Department of Physical Medicine and Rehabilitation, Lexington, KY.
Background:
Complex regional pain syndrome (CRPS) can be a debilitating source of pain and is characterized by a combination of sensory, motor, vasomotor, and autonomic abnormalities. Neuromodulation can serve as a therapeutic intervention for groin CRPS.
Case Report:
Two patients with refractory CRPS in the groin and perineum underwent bilateral dorsal root ganglion (DRG) stimulation at L1 and S2. Both patients had reduction (> 70%) in their pain with lasting (> 6 months) relief.
Conclusions:
CRPS can lead to changes in phenotype and function of the DRG. Stimulation of the DRG can block the passage of impulse trains where peripheral and central pathways of pain are modulated, resulting in improved symptoms and quality of life. Groin and perineal pain, refractory to conventional interventions, can be successfully treated with DRG stimulation.
