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OPTIC DISK PIT MACULOPATHY-LIKE RETINOSCHISIS WITHOUT A CLINICALLY VISIBLE OPTIC DISK PIT
Ye Ji Kim1, Nicolò Ribarich2,3, Giuseppe Querques2,3
1Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine, Seoul, Republic of Korea.
Retina (Philadelphia, Pa.)
|June 27, 2025
Summary
Peripapillary retinoschisis (PPRS) without a visible optic disc pit is linked to lamina cribrosa defects. Vitrectomy may improve visual acuity and central foveal thickness in these cases.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Optic Neuropathies
Background:
- Peripapillary retinoschisis (PPRS) can mimic optic disc pit maculopathy.
- Understanding PPRS without a visible optic disc pit is crucial for diagnosis and management.
Purpose of the Study:
- To characterize the structural and clinical features of PPRS without a visible optic disc pit.
- To explore potential pathogenesis and effective treatments for this condition.
Main Methods:
- Retrospective observational case series of 20 eyes in 19 patients with PPRS.
- Management groups: observation, intraocular pressure (IOP) control, and vitrectomy.
- Analysis of clinical features, optical coherence tomography (OCT) findings, and outcomes.
Main Results:
- Abnormal lamina cribrosa (LC) findings, including defects and disinsertions, were present in all 20 eyes.
- Foveal detachment occurred in 5 eyes; 8 eyes had glaucoma.
- Vitrectomy group showed significant improvement in best-corrected visual acuity (BCVA) and central foveal thickness (CFT).
Conclusions:
- Lamina cribrosa defects are associated with PPRS lacking a visible optic disc pit.
- Vitrectomy demonstrates potential as an effective treatment for PPRS in this context.
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