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Updated: Sep 17, 2025

A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors
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An NADH-controlled gatekeeper of ATP synthase

Fabian Schildhauer1, Petra S J Ryl1, Simon M Lauer2

  • 1Technische Universität Berlin, Chair of Bioanalytics, 10623 Berlin, Germany.

Molecular Cell
|June 27, 2025
PubMed
Abstract

Keywords:
AIFM1AK2ATP synthesisOXPHOSadenylate kinase 2apoptosis-inducing factor 1cell signalingcrosslinking mass spectrometryenergy metabolismmitochondriamitochondrialoxidative phosphorylationprotein structureprotein-protein interaction

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