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Sclerotherapy With Polidocanol Is Highly Effective for Treating Oral Cavernous Hemangiomas in Children
Li-Na Han1, Yu-Bo Wang1, Rong-Xiang Tian2
1Department of Stomatology, Central Hospital of Qinghe, Xingtai, P.R. China.
Insights
Polidocanol sclerotherapy effectively treats pediatric oral cavity hemangiomas, achieving 95% regression. This safe and simple treatment is recommended over traditional pingyangmycin therapy for these non-resolving vascular tumors.
Area of Science:
- Pediatric surgery
- Vascular anomalies
- Oral medicine
Background:
- Pediatric cavernous hemangiomas over age 2 rarely resolve spontaneously.
- Oral cavity hemangiomas often necessitate intervention.
- Traditional treatments have limitations.
Purpose of the Study:
- To compare polidocanol sclerotherapy with pingyangmycin therapy.
- To evaluate treatment outcomes for oral cavity hemangiomas in children.
Main Methods:
- Ultrasound-monitored polidocanol sclerotherapy was used.
- 21 pediatric patients (ages 2-11) with oral hemangiomas were treated.
- Outcomes were compared to historical pingyangmycin data.
Main Results:
- 95% total tumor regression was achieved with polidocanol (20/21 cases).
- Polidocanol success rate significantly exceeded pingyangmycin (<50%).
- Mild, transient side effects (swelling, pain, ulceration) were similar in both groups.
Conclusions:
- Polidocanol sclerotherapy is an effective and safe treatment for pediatric oral hemangiomas.
- It offers a simpler alternative to conventional therapies.
- Recommended for replacing pingyangmycin treatment.
Background/Aim:
Cavernous hemangiomas in children older than 2 years will unlikely resolute and therefore, frequently require treatment. The aim of the study was to comparatively evaluated the outcome of the sclerotherapy with polidocanol and the conventional pingyangmycin therapy for thick cavernous hemangiomas in the oral cavity in children.
Patients And Methods:
We treated a total of 21 cavernous hemangiomas in the oral cavity (majority on the tongue) of children aged 2-11 years by means of a sclerotherapy using an anesthetic agent polidocanol under ultra-sound monitoring.
Results:
Total regression of the tumors was achieved in 20 cases, corresponding to a success rate of 95%, significantly (p=0.0005) higher than that achieved by the conventional pingyangmycin therapy, which was <50%. No severe complication was observed, while mild and transit ones such as local swelling, pain, and ulceration were reported by both groups at similar frequency (10-20%).
Conclusion:
Sclerotherapy using polidocanol provides an effective, safe, and relatively simple treatment for hemangiomas in the oral cavity of children and may be recommended to replace the conventional pingyangmicine treatment.
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