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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

452
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
452
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

381
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
381
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

332
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
332
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

207
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
207
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

246
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
246
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

32
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
32

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Updated: Sep 17, 2025

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Severe Calcific Constrictive Pericarditis From Remotely Treated Tuberculosis.

Harry Choi1, Marcos Ferrandez-Escarabajal1, Tara Naib1

  • 1Mount Sinai Fuster Heart Hospital, New York, New York, USA.

JACC. Case Reports
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Summary

Tuberculosis can cause constrictive pericarditis, a serious heart condition, even decades after initial infection. Early diagnosis and treatment, including pericardiectomy, significantly improve patient outcomes.

Keywords:
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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Constrictive pericarditis is a rare but severe complication of tuberculosis (TB).
  • TB pericarditis poses a significant risk, particularly in non-endemic regions.
  • Delayed presentation of TB-related constrictive pericarditis is possible.

Observation:

  • A 40-year-old male with a childhood history of treated TB presented with heart failure.
  • Severe calcific constrictive pericarditis, attributed to remote TB, was diagnosed.
  • The patient experienced biventricular failure and volume overload due to the condition.

Findings:

  • Guideline-directed medical therapy and diuresis were initiated for patient optimization.
  • The patient underwent successful pericardiectomy, leading to symptom resolution.
  • Significant improvements in quality of life were observed post-surgery.

Implications:

  • This case highlights the potential for TB to cause constrictive pericarditis long after initial infection.
  • Multimodality imaging is crucial for accurate diagnosis and treatment planning.
  • Prompt surgical intervention (pericardiectomy) can effectively manage severe cases and improve prognosis.