Usefulness of Echocardiography Contrast Agents for the Detection of Residual Leak After Percutaneous LAA Closure

Abdellaziz Dahou1, Nathanael Tran1, Jacob Dal-Bianco1

  • 1Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

JACC. Case Reports
|June 27, 2025
PubMed

Insights

Echo contrast agents effectively detect residual leaks after left atrial appendage closure (LAAC) when standard methods are inconclusive. This low-cost tool aids in diagnosing leaks, improving patient management after LAAC procedures.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Percutaneous left atrial appendage closure (LAAC) is a common procedure for stroke prevention in atrial fibrillation.
  • Residual leaks post-LAAC increase thromboembolic event risk, necessitating accurate detection.
  • Cardiac computed tomography (CCT) and transesophageal echocardiography (TEE) are used for follow-up, but diagnosis can be challenging.

Observation:

  • A 78-year-old woman with atrial fibrillation and prior transient ischemic attack underwent successful LAAC with a WATCHMAN device.
  • Initial TEE showed no residual leak; anticoagulation was discontinued.
  • Subsequent TEE revealed an abnormal gap around the device, with color Doppler suggesting a leak, but diagnosis remained uncertain.

Findings:

  • Contrast-enhanced TEE definitively diagnosed a residual leak after LAAC.
  • The echo contrast agent provided clear visualization, aiding in management decisions.
  • This case highlights the utility of contrast agents in challenging TEE evaluations for LAAC leaks.

Implications:

  • Echo contrast agents offer a valuable, low-cost alternative to CCT for detecting residual LAAC leaks.
  • This technique can improve diagnostic accuracy in cases where color Doppler is inconclusive.
  • Wider adoption of contrast-enhanced TEE could enhance post-LAAC monitoring and patient outcomes.
Abstract