Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intermittent tracheostomy in sheep.

R Dueck, T M Davidson, M Rathbun

    Laboratory Animal Science
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    A new modified tracheostomy technique in sheep prevents tracheal stenosis, a common complication in respiratory studies. This surgical approach ensures better animal welfare and reliable research outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Results of TRIO-15, a multicenter, open-label, phase II study of the efficacy and safety of ganitumab in patients with recurrent platinum-sensitive ovarian cancer.

    Gynecologic oncology·2023
    Same author

    Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer.

    Gynecologic oncology·2021
    Same author

    Progressive melanoma versus tumor melanosis: is imaging enough?

    Annals of oncology : official journal of the European Society for Medical Oncology·2021
    Same author

    Sportsmedicine forum.

    The Physician and sportsmedicine·2016
    Same author

    Rattlesnakes: The Animal and the Venom (Part 1 of 2).

    The Physician and sportsmedicine·2016
    Same author

    First Aid and Management of Rattlesnake Bites (Part 2 of 2).

    The Physician and sportsmedicine·2016
    Same journal

    Major histocompatibility haplotype does not impact the course of experimentally induced murine vaginal candidiasis.

    Laboratory animal science·2000
    Same journal

    Pathologic changes associated with use of tribromoethanol (avertin) in the Sprague Dawley rat.

    Laboratory animal science·2000
    Same journal

    Depressive effects of anesthesia or sedation on exocrine pancreatic function in pigs.

    Laboratory animal science·2000
    Same journal

    Effects of histamine, carbachol, and methacholine on maximal expiratory lung mechanics in goats.

    Laboratory animal science·2000
    Same journal

    Comparison of three treatments for control of ear mites in ferrets.

    Laboratory animal science·2000
    Same journal

    Comparison of two systems for tibial external fixation in rabbits.

    Laboratory animal science·2000
    See all related articles

    Area of Science:

    • Veterinary Surgery
    • Animal Models
    • Respiratory Physiology

    Background:

    • Tracheal stenosis is a significant complication in sheep undergoing tracheostomy for respiratory studies.
    • Existing canine tracheostomy techniques can lead to severe tracheal stenosis in sheep.
    • Preventing tracheal stenosis is crucial for animal welfare and study validity.

    Purpose of the Study:

    • To design and evaluate a modified tracheostomy procedure in sheep.
    • To prevent the development of severe tracheal stenosis.
    • To provide a reliable surgical method for respiratory function studies in sheep.

    Main Methods:

    • A modified tracheostomy technique involving an intercartilaginous tracheal slit with mucosa-to-skin apposition was developed.
    • The procedure was performed on 19 sheep for respiratory function studies.

    Related Experiment Videos

  • A control group of 20 sheep underwent a different tracheostomy technique involving excision of tracheal rings.
  • Main Results:

    • The modified tracheostomy procedure resulted in no significant tracheal stenosis at postmortem evaluation.
    • In contrast, 5 out of 20 sheep (25%) that underwent tracheal ring excision experienced severe tracheal stenosis.
    • The intercartilaginous slit technique demonstrated superior outcomes in preventing stenosis.

    Conclusions:

    • The modified intercartilaginous tracheal slit tracheostomy is effective in preventing tracheal stenosis in sheep.
    • This technique offers a safer alternative for sheep requiring tracheostomy for research purposes.
    • Improved surgical methods are essential for enhancing animal welfare in physiological research.