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Updated: Sep 17, 2025

Deep Learning-Based Segmentation of Cryo-Electron Tomograms
Published on: November 11, 2022
DeepEM Playground: Bringing deep learning to electron microscopy labs
Hannah Kniesel1, Poonam Poonam1, Tristan Payer1
1Visual Computing Group, Ulm University, Ulm, Germany.
Abstract:
Deep learning (DL) has transformed image analysis, enabling breakthroughs in segmentation, object detection, and classification. However, a gap persists between cutting-edge DL research and its practical adoption in electron microscopy (EM) labs. This is largely due to the inaccessibility of DL methods for EM specialists and the expertise required to interpret model outputs. To bridge this gap, we introduce DeepEM Playground, an interactive, user-friendly platform designed to empower EM researchers - regardless of coding experience - to train, tune, and apply DL models. By providing a guided, hands-on approach, DeepEM Playground enables users to explore the workings of DL in EM, facilitating both first-time engagement and more advanced model customisation. The DeepEM Playground lowers the barrier to entry and fosters a deeper understanding of deep learning, thereby enabling the EM community to integrate AI-driven analysis into their workflows more confidently and effectively.
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