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Hospitalizations for Infective Endocarditis in Children: 15-Year Analysis
Margarida Dias1, Rita Amorim1, Ana Luísa Correia2
1Department of Pediatrics. Centro Hospitalar Universitário de São João. Porto. Portugal.
Acta Medica Portuguesa
|June 28, 2025
Summary
Hospitalizations for infective endocarditis (IE) in children are increasing, with Staphylococci becoming more frequent. Awareness is crucial for pediatric patients with heart disease and prosthetic material.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Clinical Epidemiology
Background:
- Infective endocarditis (IE) presents diagnostic challenges and carries significant morbidity and mortality.
- A comprehensive analysis of pediatric IE hospitalizations was conducted at a tertiary hospital.
Purpose of the Study:
- To analyze trends and characteristics of pediatric infective endocarditis hospitalizations.
- To identify key clinical features, microbiological profiles, and outcomes in pediatric IE cases.
Main Methods:
- Retrospective study of pediatric IE hospitalizations from 2008-2022.
- Review of clinical presentation, treatment, complications, outcomes, and causative microorganisms.
- Inclusion of data on patient demographics, comorbidities, diagnostic methods, and interventions.
Main Results:
- 27 pediatric IE hospitalizations observed, with an increasing trend in recent years.
- High prevalence of underlying heart disease (88.9%), particularly congenital (95.8%), and prosthetic material (59.3%).
- Common complications included embolic events (44.4%); Staphylococcus aureus was the most frequent pathogen (48.1%).
Conclusions:
- A rising trend in pediatric IE hospitalizations was noted.
- While Streptococci remain prevalent, Staphylococci are increasingly identified as causative agents.
- Vigilance for IE is essential in pediatric patients with cardiac conditions and prosthetic devices.
Keywords:
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