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Related Experiment Videos

The elgiloy microelectrode: fabrication techniques and characteristics.

J W Ashford, K L Coburn, J M Fuster

    Journal of Neuroscience Methods
    |September 1, 1985
    PubMed
    Summary

    We developed improved microelectrodes from elgiloy wire for neural recording. These durable, glass-insulated electrodes enable precise extracellular recordings and histological verification.

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    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Materials Science

    Background:

    • Elgiloy wire, a cobalt-chromium alloy, has been used for microelectrodes.
    • Previous fabrication methods lacked detailed procedures for optimization.

    Purpose of the Study:

    • To refine fabrication techniques for glass-insulated microelectrodes.
    • To enhance electrode performance for extracellular neural recording.

    Main Methods:

    • Modified elgiloy wire hardening and etching.
    • Precise control of tip size, geometry, and exposure.
    • Molten solder glass insulation.
    • Tip impedance adjustment.

    Main Results:

    • Fabrication procedures detailed for consistent microelectrode production.

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  • Electrodes suitable for single/multiple unit and evoked potential recording.
  • High durability for chronic preparations.
  • Iron content facilitates Prussian blue histological marking.

    • Conclusions:

    • Modified fabrication yields robust, high-performance microelectrodes.
    • These electrodes are effective for chronic neural recording in animal models.
    • Prussian blue staining offers reliable verification of recording sites.