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Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
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Debate About the Free Testosterone Hypothesis: Useful Tool or Misguided Mirage?

Bradley D Anawalt1, David J Handelsman2

  • 1Medicine, University of Washington School of Medicine, Box 356420, Seattle, WA 98195, USA.

The Journal of Clinical Endocrinology and Metabolism
|June 28, 2025
PubMed
Summary

This debate explores the free testosterone hypothesis in male hypogonadism. While some support its measurement, others question its validity and accurate clinical assessment.

Keywords:
diagnosisfree testosteronefree testosterone hypothesismale hypogonadismsex hormone–binding globulin

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