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Related Concept Videos

Pigmentation01:19

Pigmentation

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Dermis
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Updated: Sep 17, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Updates in Dermoscopy for Pigmented Lesions.

Noah Musolff1, Madeline Tchack2, Zaima Sohail Chaudhry3

  • 1Department of Dermatology, Rao Dermatology, 900 Broadway, New York, NY 10003, USA.

Dermatologic Clinics
|June 28, 2025
PubMed
Summary
This summary is machine-generated.

Dermoscopy improves skin lesion diagnosis, especially for pigmented lesions. Recent updates to diagnostic algorithms like the ABCDE rule and 7-point checklist enhance melanoma and other skin cancer detection.

Keywords:
Dermoscopic algorithmsDermoscopyMalignant melanomaMelanocytic neviPigmented lesions

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Area of Science:

  • Dermatology
  • Medical Diagnostics

Background:

  • Dermoscopy is a crucial non-invasive tool for skin lesion examination.
  • Accurate diagnosis of pigmented lesions is vital for effective treatment.

Purpose of the Study:

  • To provide updated diagnostic algorithms for pigmented lesions.
  • To highlight novel diagnostic features for various skin cancers.

Main Methods:

  • Review of key diagnostic algorithms: ABCDE rule, 7-point checklist, ASAP algorithm.
  • Analysis of new dermoscopic patterns for specific lesions.

Main Results:

  • Significant advancements in diagnostic accuracy for pigmented lesions.
  • Identification of characteristic patterns for malignant melanoma, melanocytic nevi, and pigmented basal cell carcinoma.

Conclusions:

  • Updated algorithms enhance the diagnostic capabilities of dermoscopy.
  • New features improve the differentiation of benign and malignant pigmented skin lesions.