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Spina Bifida

Andrew R McCoy1, Lydia Singerman2, Neha Anand3

  • 1Division of Rehabilitation Medicine, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3615 Civic Center Boulevard, Room 1419A, Philadelphia, PA, USA.

Physical Medicine and Rehabilitation Clinics of North America
|June 28, 2025
PubMed

Insights

Spina bifida (SB) is a common neural tube defect. This overview details the complex, multidisciplinary management of myelomeningocele, the most severe form of SB, addressing its neurological, urinary, gastrointestinal, and musculoskeletal complications.

Area of Science:

  • Pediatric Neurology
  • Developmental Biology
  • Clinical Medicine

Background:

  • Spina bifida (SB) represents the most frequent neural tube defect.
  • Myelomeningocele, the most severe SB form, causes significant sequelae affecting multiple systems.
  • Management necessitates a coordinated, multidisciplinary approach.

Purpose of the Study:

  • To provide a comprehensive overview of spina bifida management.
  • To highlight the complexities in caring for children with myelomeningocele.
  • To outline the multidisciplinary coordination required for SB care.

Main Methods:

  • Literature review of spina bifida management strategies.
  • Synthesis of current clinical guidelines and research.
  • Overview of common complications and their treatments.

Main Results:

  • Identification of key areas in SB management: neurological, urinary, gastrointestinal, and musculoskeletal.
  • Emphasis on the critical role of interdisciplinary collaboration.
  • Discussion of the long-term sequelae and ongoing care needs.

Conclusions:

  • Effective spina bifida care requires integrated management across specialties.
  • Addressing the multifaceted complications of myelomeningocele is crucial.
  • Continuous coordination ensures optimal outcomes for affected children.

Keywords:
Chiari II malformationHydrocephalusMyelomeningoceleNeurogenic bladderNeurogenic bowelSpina bifida

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