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Related Experiment Videos

[Intestinal perforations in the newborn infant].

K H Muhrer, R D Filler

    Langenbecks Archiv Fur Chirurgie
    |January 1, 1985
    PubMed
    Summary

    This study analyzed 16 neonates with gastrointestinal perforations, finding the ileo-cecal region most common. Sepsis and septic complications led to a 44% mortality rate in these newborns.

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    Area of Science:

    • Pediatric Surgery
    • Neonatal Medicine
    • Gastrointestinal Diseases

    Context:

    • Gastrointestinal perforations in neonates present significant surgical challenges.
    • This study reviews a cohort of neonates treated for gastrointestinal perforations.
    • The period of study spans from 1976 to March 1985.

    Purpose:

    • To analyze the causes, common sites, and outcomes of neonatal gastrointestinal perforations.
    • To evaluate the surgical management strategies employed for these conditions.
    • To identify factors contributing to mortality in affected neonates.

    Summary:

    • Sixteen neonates with gastrointestinal perforations were treated, with the ileo-cecal region being the most frequent site.
    • Common causes included intestinal obstruction, necrotizing enterocolitis, and ischemic perforations.
    • Surgical procedures were tailored to perforation site, cause, and the neonate's general condition.

    Impact:

    • Mortality rate was 44% (7 out of 16 neonates), primarily due to sepsis and septic complications.
    • Highlights the critical impact of sepsis on outcomes for neonates with gastrointestinal perforations.
    • Informs surgical decision-making and emphasizes the need for aggressive sepsis management in neonatal surgical emergencies.

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