Related Experiment Video
Updated: Sep 22, 2026

Pseudofracture: An Acute Peripheral Tissue Trauma Model
Published on: April 18, 2011
Abstract:
The diagnosis of multiple organ failure is based upon the sequential occurrence of failure of vital organ functions within a short period of time (lung, kidney, circulatory system, gastrointestinal tract, liver, metabolism, hemostasis). Underlying diseases are polytrauma, high risk surgical procedures, acute abdominal complications. Sepsis is the main pathogenetic factor. The mortality is 60-80% and in patients with abdominal sepsis plus acute renal failure and dialysis plus acute lung failure and artificial ventilation up to 100%. Intensive care is therefore focussed upon prophylaxis, predominantly shock therapy and surgical treatment of sepsis.
Related Concept Videos
Pathophysiology of Heart Failure
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Cellular Injury IV: Necrosis
Cirrhosis II: Pathophysiology
Portal Hypertension
Acute Pancreatitis II: Pathophysiology

