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Global Variation in Out-of-Pocket Payments for Cancer Surgery
Joana F F Simoes1, Maria Picciochi1, Adesoji Ademuyiwa1,2
1NIHR Global Health Research Unit on Global Surgery, University of Birmingham, Birmingham, UK.
World Journal of Surgery
|June 29, 2025
Summary
Patients in low-income countries face high out-of-pocket payments for cancer surgery. Developing health insurance plans is crucial to prevent catastrophic expenditure and improve access to essential cancer care.
Area of Science:
- Global Health
- Surgical Oncology
- Health Economics
Background:
- Cancer surgery is a critical intervention for a leading global health challenge.
- High costs associated with cancer treatment pose significant financial burdens worldwide.
- Understanding out-of-pocket payments (OOPP) is essential for assessing financial toxicity in cancer care.
Purpose of the Study:
- To analyze and compare out-of-pocket payments for cancer surgery across different country income groups.
- To identify factors associated with OOPP for cancer surgery in low- and middle-income countries.
Main Methods:
- Secondary analysis of an international prospective cohort study.
- Included 24,498 patients from 108 countries undergoing cancer surgery in October 2020.
- Compared OOPP rates across high-income (HICs), upper-middle-income (UMICs), lower-middle-income (LMICs), and low-income countries (LICs).
- Used logistic regression to identify predictors of OOPP in LMICs.
Main Results:
- Overall, 6.4% of patients incurred OOPP for cancer surgery.
- OOPP rates significantly increased with lower country income: 0.5% (HICs) to 48.1% (LICs).
- Male sex and elective surgery were independently associated with higher OOPP in LMICs.
Conclusions:
- Patients in LMICs face a substantial risk of catastrophic expenditure due to OOPP for cancer surgery.
- Governments should implement health insurance plans covering elective cancer surgery, involving various stakeholders.
- Further research is needed to understand gender-related disparities in out-of-pocket spending and healthcare access.
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