Related Experiment Video
Updated: Sep 17, 2025
Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
Published on: August 6, 2019
Impact of Inflammatory Bowel Disease on Perioperative Complications in Patients Undergoing Cervical Spine Fusion
Xuyang Yan1, Xiaorong Yang1, Hao Xie2
1School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Objective:
The global prevalence of inflammatory bowel disease (IBD) is increasing rapidly, and its systemic inflammation and immune dysregulation may affect surgical outcomes. However, the impact of IBD on perioperative complications in cervical spine fusion has never been reported. This study aimed to investigate the association between IBD and perioperative complications of cervical spine fusion using the National Inpatient Sample database and analyze the related risk factors.
Methods:
Data from patients undergoing cervical spine fusion between 2010 and 2019 were extracted using International Classification of Diseases, Ninth and Tenth Edition, Clinical Modification codes. Patients under the age of 18 were excluded. Patients were grouped based on the presence or absence of IBD, and demographic, hospital, comorbidity, and perioperative complication data were compared. Statistical analyses included Pearson χ2 test, Wilcoxon rank-sum test, and logistic regression.
Results:
A total of 350,775 patients who underwent cervical spine fusion were enrolled, with 1838 (0.52%) having comorbid IBD. The prevalence of IBD increased from 0.4% in 2010 to 0.8% in 2019. The presence of IBD was associated with an increased risk of specific perioperative complications, including dysphagia (odds ratio [OR] = 1.49), urinary tract infection (OR = 1.31), acute kidney injury (OR = 1.87), sepsis (OR = 1.51), pulmonary embolism (OR = 2.40), and acute myocardial infarction (OR = 2.04).
Conclusions:
The prevalence of IBD among patients undergoing cervical spine fusion is increasing, and patients with IBD face higher risks of specific perioperative complications. Spine surgeons should conduct more detailed risk assessments and adjust perioperative management accordingly.
More Related Videos
Related Concept Videos
01:21Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
01:30Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
01:17Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
01:22Aneurysm IV: Nursing Management
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...