Related Experiment Video
Updated: Sep 17, 2025

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
Automated insulin delivery for safe fasting and exercise during Ramadan in patients with type 1 diabetes: The active
Khaled Baagar1, Hamda Ali1, Fateen Ata1
1Technology and Diabetes Unit, Department of Diabetes and Endocrinology, Hamad Medical Corporation, Doha, Qatar.
Aims:
To evaluate the safe and effective use of the MiniMed™ 780G Advanced Hybrid Closed-Loop system (AHCLS) in adults with type 1 diabetes mellitus (T1DM) during Ramadan fasting combined with structured Moderate-Intensity Exercise (MIE) followed by the non-fasting month (Shawwal) with continued MIE.
Methods:
This prospective, single-arm interventional study recruited 34 adults with T1DM using the MiniMed™ 780G. Participants performed MIE during non-fasting hours in Ramadan and continued it in Shawwal. Analyzed parameters included glycemic control, insulin requirements, usage of the MiniMed™ 780G system, metabolic parameters, and treatment satisfaction.
Results:
Median time below range (<70 mg/dL) remained stable (1.0 %) across Ramadan and Shawwal (p = 0.39). Time in range (70-180 mg/dL) was significantly higher during Ramadan (70.5 %) than Shawwal (68.5 %, p = 0.0134), with a less median time above range(>180 mg/dL) in Ramadan (29 %) compared to Shawwal (30 %) (p = 0.0088). No severe hypoglycemia or DKA occurred. Participants demonstrated high treatment satisfaction and SmartGuard mode usage, with good adherence to fasting and exercise.
Conclusions:
Adults with T1DM can safely fast during Ramadan and exercise using the MiniMed™ 780G to manage diabetes. Findings from this study build on the real-world evidence to enhance clinical guidelines for optimal T1DM care using advanced technology.
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Hypoglycemia and Glucagon
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

