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Postpoliomyelitis muscle pseudohypertrophy.

T E Bertorini, M Igarashi

    Muscle & Nerve
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    This study details a rare case of bilateral lower limb muscle pseudohypertrophy in a 62-year-old patient with a history of childhood poliomyelitis. The condition resulted from excess adipose tissue and muscle work hypertrophy.

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    Area of Science:

    • Neurology
    • Muscle Physiology

    Background:

    • Poliomyelitis is a viral disease that can cause muscle weakness and paralysis.
    • Long-term sequelae of poliomyelitis can include muscle atrophy and functional deficits.

    Observation:

    • A 62-year-old patient presented with bilateral lower limb muscle pseudohypertrophy.
    • The patient had a history of acute paralytic poliomyelitis in early childhood.

    Findings:

    • Histological examination revealed that pseudohypertrophy was predominantly due to adipose tissue infiltration, replacing muscle fibers.
    • Work hypertrophy of remaining muscle fibers contributed partially to the enlarged muscle bulk.

    Implications:

    • This case highlights an unusual long-term complication of poliomyelitis, emphasizing the role of adipose tissue in muscle pseudohypertrophy.

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  • Understanding these mechanisms is crucial for managing long-term neurological and musculoskeletal conditions.