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First reported case of axillary Angiolymphoid hyperplasia with eosinophilia: a rare localization and literature
Dyala Sayed Ahmed1, Zeinab Mustafa Asmar1, Moatasem Hussein Al-Janabi2
1Department of Dermatology and sexually transmitted disease, Tishreen University Hospital, Lattakia, 041, Syria.
Abstract:
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vasoproliferative disorder that commonly affects the scalp and periauricular region. It presents as solitary or multiple erythematous papules or nodules, typically in young to middle-aged adults. The etiology remains unclear, with trauma, infections, and hormonal influences considered possible triggers. Here, we report a rare case of ALHE in a 72-year-old male with multiple scalp nodules and a solitary lesion in the axilla, an unusual anatomical site. Histopathological examination confirmed ALHE. Surgical excision was performed, with no recurrence at six months. To our knowledge, this is the first documented case of axillary ALHE, expanding the spectrum of its clinical presentation.

