Related Experiment Video
Updated: Sep 17, 2025
10:21
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
Published on: March 3, 2023
1.5K
Struma ovarii mimicking ovarian malignancy: a case report
Giulia Bruni1, Marta Tripepi2, Ana Gomes da Costa3
1Department of Medical Sciences, University of Ferrara, Ferrara 4421, Italy.
Journal of Surgical Case Reports
|June 30, 2025
Summary
Struma ovarii, a rare ovarian teratoma, can mimic ovarian cancer with symptoms like ascites and elevated CA125. Surgical diagnosis confirmed a benign struma ovarii in this case, highlighting its potential to be misdiagnosed.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Background:
- Struma ovarii is a rare monodermal ovarian teratoma, predominantly mature thyroid tissue.
- It can present atypically, mimicking advanced ovarian malignancy.
- Elevated serum CA125 and ascites are key indicators that can mislead diagnosis.
Observation:
- A 38-year-old woman presented with a complex ovarian mass, ascites, and elevated CA125.
- Initial clinical presentation strongly suggested ovarian carcinoma.
- Surgical intervention was performed for diagnosis and management.
Findings:
- Histopathological examination confirmed the ovarian mass as benign struma ovarii.
- The patient's symptoms of ascites and elevated CA125 resolved post-surgery.
- This case highlights the diagnostic challenge posed by struma ovarii.
Implications:
- Struma ovarii requires consideration in the differential diagnosis of ovarian masses, even with malignancy-suggestive features.
- Accurate diagnosis is crucial to avoid unnecessary aggressive treatment for ovarian cancer.
- Further research into the specific markers and imaging characteristics of struma ovarii may improve early detection.
