Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Metastases to the nervous system].

P Berlit, H Gänshirt

    Der Nervenarzt
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Metastases frequently affect the brain and spine, often originating from lung or breast cancer. In many cases, nervous system metastases are the initial indicator of cancer, impacting diagnosis and treatment strategies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Management of systemic lupus erythematosus-Including secondary antiphospholipid syndrome, fertility and pregnancy : S3 guidelines of the German Society for Rheumatology and Clinical Immunology and the German Society for Neurology (DGN), German Society for Internal Medicine (DGIM), German Cardiac Society (DGK), Society for Thrombosis and Hemostasis Research (GTH), German Society for Hematology and Medical Oncology (DGHO), German Society for Pediatric and Adolescent Medicine (DGKJ), Society for Pediatric and Adolescent Rheumatology (GKJR), German Society for Nephrology (DGfN), German Society for Pneumology and Ventilation Medicine (DGP), German Rheumatism League National Association, Lupus Erythematosus Self-help Community, German Dermatological Society (DDG). Version: 1.2].

    Zeitschrift fur Rheumatologie·2025
    Same author

    [Diagnosis and treatment of ANCA-associated vasculitis : S3 guideline of the German Society for Rheumatology and Clinical Immunology e. V. (DGRh) and German Society for Internal Medicine e. V. (DGIM), German Society for Nephrology e. V. (DGfN), German Society for ENT Medicine and Head and Neck Surgery e. V. (DGHNO-KHC), German Ophthalmological Society e. V. (DOG), German Society for Neurology e. V. (DGN), German Society for Pneumology and Respiratory Medicine e. V. (DGP), German Society for Pathology e. V. (DGP), German Radiological Society, Society for Medical Radiology e. V. (DRG), Federal Association of German Pathologists, Federal Kidney Association e. V., German Rheumatism League Federal Association e. V.]

    Zeitschrift fur Rheumatologie·2025
    Same author

    [Diagnosis and treatment of ANCA-associated vasculitis : SHORT VERSION of the S3 guideline of the German Society for Rheumatology and Clinical Immunology e. V. (DGRh) and German Society for Internal Medicine e. V. (DGIM), German Society for Nephrology e. V. (DGfN), German Society for Otorhinolaryngology and Head and Neck Surgery e. V. (DGHNO-KHC), German Ophthalmological Society e. V. (DOG), German Society for Neurology e. V. (DGN), German Society for Pneumology and Respiratory Medicine e. V. (DGP), German Society for Pathology e. V. (DGP), German Radiological Society, Society for Medical Radiology e. V. (DRG), Federal Association of German Pathologists, Federal Kidney Association e. V., German Rheumatism League Federal Association e. V.]

    Zeitschrift fur Rheumatologie·2025
    Same author

    [German S1 Guideline Long-/Post-COVID].

    Pneumologie (Stuttgart, Germany)·2022
    Same author

    [S2k Guideline - Recommendations for Inpatient Therapy of Patients with COVID-19].

    Pneumologie (Stuttgart, Germany)·2021
    Same author

    Historical review: a short history of German neurology - from its origins to the 1940s.

    Neurological research and practice·2020
    Same journal

    [When brain abscesses run in the family…].

    Der Nervenarzt·2026
    Same journal

    [Digital health applications and adherence in depression: a qualitative study from the perspective of healthcare providers].

    Der Nervenarzt·2026
    Same journal

    Der Nervenarzt·2026
    Same journal

    [Rare genetic diseases with frequent mental symptoms].

    Der Nervenarzt·2026
    Same journal

    Der Nervenarzt·2026
    Same journal

    Der Nervenarzt·2026
    See all related articles

    Area of Science:

    • Neurology
    • Oncology
    • Pathology

    Context:

    • Analysis of 353 nervous system metastases cases over 13 years in 14,350 inpatients.
    • Investigates the incidence, localization, and primary tumor origins of central and peripheral nervous system metastases.

    Purpose:

    • To characterize the patterns of nervous system metastases, including location, frequency, and associated primary tumors.
    • To explore the clinical presentation and diagnostic implications of nervous system metastases.

    Summary:

    • Intracranial metastases (79.6%) predominated over spinal (14.7%) and peripheral (2.6%) sites, with solitary tumors being common (65.7%).
    • Bronchial carcinoma (26.6%) and breast cancer (19.5%) were the most frequent primary tumors. Nervous system metastases were the first sign of malignancy in one-third of cases.

    Related Experiment Videos

  • Focal deficits were more common than intracranial hypertension in cerebral metastases, and spinal metastases caused CSF blockade in 20%.

    • Impact:

    • Highlights the significant role of nervous system metastases as an early sign of cancer, influencing diagnostic timelines.
    • Provides insights into the correlation between primary tumor types and metastasis location, aiding in targeted diagnostic approaches.
    • Underscores the clinical manifestations and complications associated with brain and spinal metastases, informing patient management.