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Updated: Sep 17, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Acid-triggered cascade cyclization pathways of enynes: A rapid access to fused polycyclic products
Komal Goel1, Divya Shree V1, Gedu Satyanarayana1
1Department of Chemistry, Indian Institute of Technology, Hyderabad, Kandi, Sangareddy, 502284, Telangana, India. gvsatya@chy.iith.ac.in.
Abstract:
Herein, we present a novel acid-triggered cyclization of enyne biaryl systems, producing discrete phenanthrene-fused polycyclic (tri-/tetra-/penta-cyclic) products, depending upon the stereoelectronic effects of substituents. Notably, the accomplished pentacyclic structures constitute the complete core structures of natural products, namely clostrubin and borolithochromes, offering a rapid synthetic route. In addition, the absorption and emission properties of the synthesized products have been studied.
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