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Updated: Sep 17, 2025

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
Published on: January 19, 2020
Cerebral Autoregulation in Neonates: Physiology and Beyond
Aimann Surak1, Georg M Schmölzer2, Khorshid Mohammad3
1Philip C. Etches Neonatal Intensive Care Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada.
Abstract:
Neonatal cerebral hemodynamics represents a complex process affected by dynamic circulatory changes. Understanding the pathophysiology and factors that may affect cerebral blood flow in neonates is crucial to addressing the circulatory mechanism for neonatal brain injury. Studies have described multiple tools for monitoring cerebral blood flow; however, these are limited by the impracticality of using invasive tools. In this review, we explain the physiology of neonatal cerebral autoregulation with a focus on the transitional period and summarize the currently available methods for monitoring.
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