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Related Concept Videos

Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
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Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

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Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
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Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

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Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
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CNS Depressants: Alcohol and Nicotine01:27

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Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
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Insomnia01:27

Insomnia

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Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
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CNS Depressants: Barbiturates and Benzodiazepines01:14

CNS Depressants: Barbiturates and Benzodiazepines

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CNS depressants include drugs from the category of barbiturates and benzodiazepines. They are valuable medications for managing anxiety disorders and insomnia. Barbiturates, once used to induce and maintain sleep, have been replaced mainly by benzodiazepines due to barbiturate's toxicity, tolerance, and overdose risks. They interact with GABAA receptors, leading to sedation at low doses and potentially coma and death at higher doses. Phenobarbital, a long-acting barbiturate, possesses...
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Related Experiment Video

Updated: Sep 8, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Within-Person Bidirectional Relations Between Sleep Problems and Alcohol, Cannabis, and Co-Use Problems in a

Tess K Drazdowski1,2, Lourah Kelly3, Nicholas R Livingston4

  • 1Chestnut Health Systems, Eugene, Oregon, USA.

Substance Use & Misuse
|July 1, 2025
PubMed
Summary
This summary is machine-generated.

Many adults use alcohol and cannabis for sleep, but this study found that alcohol and cannabis use problems predict future sleep problems. Disseminating sleep interventions to adults with co-use is crucial.

Keywords:
alcoholcannabisco-usemarijuanasleepwithin-person

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Area of Science:

  • Addiction Medicine
  • Sleep Science
  • Public Health

Background:

  • Many adults use alcohol and cannabis to aid sleep, despite known associations between sleep issues and substance use.
  • Limited understanding exists regarding the long-term, reciprocal relationships between sleep problems, alcohol use, cannabis use, and their co-use.

Purpose of the Study:

  • To investigate the bidirectional, longitudinal associations between sleep problems and alcohol problems, cannabis problems, and co-use problems in a national sample of adults.

Main Methods:

  • Secondary analysis of data from 26,072 adults in the Population Assessment of Tobacco and Health (PATH) Study (2013-2018).
  • Employed three random intercept cross-lagged panel models to examine within-person relationships over time.

Main Results:

  • Sleep problems consistently predicted subsequent sleep problems.
  • Alcohol and cannabis use problems were linked to decreased sleep problems initially, but increased sleep problems in later waves.
  • No direct longitudinal association was found between co-use problems and sleep problems, though co-users reported higher overall sleep problems.

Conclusions:

  • Large-scale sleep interventions are recommended, potentially mitigating alcohol and cannabis use problems.
  • Elevated sleep problem rates in adults with co-use necessitate further research and targeted dissemination of sleep interventions.