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Tetrahedral Deoxyribonucleic Acid-Engineered Multivalent Lysosome-Targeting Chimera for Enhanced and Dual Membrane

Haoran Zhu1, Guihua Zhang1, Yuhua Ning1

  • 1The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.

ACS Nano
|July 1, 2025
PubMed

Keywords:
LYTACaptamermultivalenttargeted protein degradationtetrahedral DNA

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