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Related Experiment Videos

Sunscreens and PUVA.

W S Douglas, R Railton, P N Newman

    Photo-Dermatology
    |August 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Sunscreen creams effectively protect skin during 8-methoxypsoralen photochemotherapy (PUVA). These UVA sunscreens may lower cancer risk, and a simple efficacy test is presented.

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    Area of Science:

    • Dermatology
    • Photobiology
    • Oncology

    Background:

    • Photochemotherapy using 8-methoxypsoralen and ultraviolet A (PUVA) is a common dermatological treatment.
    • PUVA therapy can increase the risk of skin carcinogenesis.
    • Protecting non-lesional skin during PUVA is crucial for patient safety.

    Purpose of the Study:

    • To evaluate the efficacy of sunscreen creams in protecting non-lesional skin during PUVA therapy.
    • To identify cosmetically acceptable sunscreens that offer adequate UVA protection.
    • To introduce a straightforward method for assessing sunscreen efficacy in this context.

    Main Methods:

    • Testing of sunscreen preparations on non-lesional skin in patients undergoing PUVA.
    • Assessment of UVA protection capacity of selected sunscreen formulations.

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  • Development and description of a simple efficacy testing procedure.

    • Main Results:

    • Certain sunscreen preparations, including Contralum Ultra and RoC Total, demonstrated effective UVA protection.
    • These tested sunscreens are considered cosmetically acceptable for patient use.
    • The proposed simple test can reliably assess sunscreen efficacy.

    Conclusions:

    • Effective UVA sunscreens can be utilized to protect non-lesional skin during PUVA.
    • The use of these sunscreens may mitigate the risk of carcinogenesis associated with PUVA therapy.
    • A practical method for evaluating sunscreen efficacy in this clinical setting is available.