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Updated: Sep 17, 2025

Rodent Working Heart Model for the Study of Myocardial Performance and Oxygen Consumption
Published on: August 16, 2016
Pressure drop across common LV vent catheters
Nicholas Ownbey1, Tyler Randolph1, Nicholas Majzer1
1Division of Cardiovascular Perfusion, College of Health Professions, Medical University of South Carolina, Charleston, SC, USA.
Abstract:
PurposeThis study examined the pressure drop across several LV vent catheters commonly used in adult and pediatric cardiac surgery to identify optimal vent catheters for different flows that may be required based on patient and surgical specific factors.MethodsIn an experimental set up, 5 sizes of Medtronic DLP Left Heart vent catheters (10Fr, 13Fr, 15Fr, 18Fr, and 20Fr) were tested using a blood analogous solution. Flow was increased incrementally by either 5 or 10 RPMs on a roller pump and measured using a non-invasive flow sensor. Pressures were measured before and after the vent catheters and pressure drop across the catheter (ΔP) was recorded for each. Trials were done with and without a Quest Medical VRV-II safe vacuum relief valve in the circuit. This was all performed under temperature regulation at normothermia (37°C) and moderate hypothermia (28°C).ResultsAll vent catheters tested demonstrated a steady decline in pressure with increased flow. For all catheters, with and without vent vacuum relief valves (VRVs), a less negative pressure gradient was achieved at 37°C compared to 28°C at a given flow. Graphs were created for each vent catheter to aid in selection for a variety of patients.ConclusionLarger Medtronic DLP Left Heart vent catheters provide a lesser pressure drop for a given flow compared to a smaller catheter. Additionally, a greater flow may be achieved with a larger catheter before the VRV opens. VRVs should be used with left heart vent catheters as inclusion does not typically affect vent catheter performance.
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