Related Experiment Videos
[Levels of immune complexes in the blood of patients with thyrotoxicosis]
According to the present-day concepts a significant role in the development of thyrotoxicosis is played by autoimmune mechanisms, therefore a study of the problem of the content and role of the circulating immune complexes (IC) in this pathology is of interest. The IC amount was determined in the peripheral blood of 82 patients with thyrotoxicosis using precipitation with polyethylene glycol (mol. m. 6000). An elevated amount of the circulating IC was marked in 75% of the patients. Correlation between the IC content in the peripheral blood, the patients' age and the duration of disease was revealed. No variations of the indices with relation to the disease severity and duration were noted. The absence of the positive time-course of the signs determining the IC amount during thyrostatic therapy necessitates the incorporation of immunomodulators in multimodality therapy in thyrotoxicosis.
According to the present-day concepts a significant role in the development of thyrotoxicosis is played by autoimmune mechanisms, therefore a study of the problem of the content and role of the circulating immune complexes (IC) in this pathology is of interest. The IC amount was determined in the peripheral blood of 82 patients with thyrotoxicosis using precipitation with polyethylene glycol (mol. m. 6000). An elevated amount of the circulating IC was marked in 75% of the patients. Correlation between the IC content in the peripheral blood, the patients' age and the duration of disease was revealed. No variations of the indices with relation to the disease severity and duration were noted. The absence of the positive time-course of the signs determining the IC amount during thyrostatic therapy necessitates the incorporation of immunomodulators in multimodality therapy in thyrotoxicosis.