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Updated: Sep 17, 2025
Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans
Published on: July 5, 2019
Brief guide to Caenorhabditis elegans imaging and quantification
Hyemin Min1, Gyutae Park1, Seung-Jae V Lee1
1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea.
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Caenorhabditis elegans is a powerful model organism for fluorescence imaging to study gene regulation and cellular biomarkers. This concise MiniResource introduces essential imaging techniques for live and fixed C. elegans, sample preparations, microscopy, and common applications. We also outline basic image analysis workflows using open-source software. This guideline serves as a practical resource for researchers who seek implementing fluorescence imaging with C. elegans.
