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The Geometry of Survival: Left Ventricular Mass Index's Prognostic Value in Coronary Surgery

Barış Timur1, Rezan Aksoy1, Zihni Mert Duman2

  • 1Department of Cardiovascular Surgery, SBU Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Research and Training Hospital, Istanbul, Turkey.

The Thoracic and Cardiovascular Surgeon
|July 1, 2025
PubMed

Insights

Increased left ventricular mass negatively impacts long-term survival after coronary artery bypass grafting (CABG). This finding highlights the need for strategies to manage left ventricular remodeling for better surgical outcomes.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Cardiovascular Imaging

Background:

  • Left ventricular hypertrophy is a known cardiovascular risk factor.
  • Its specific impact on outcomes following coronary artery bypass grafting (CABG) requires further investigation.

Purpose of the Study:

  • To investigate the association between left ventricular mass and geometry and the prognosis of patients undergoing CABG.
  • To determine if left ventricular mass is an independent predictor of long-term outcomes after CABG.

Main Methods:

  • Retrospective analysis of 494 patients undergoing elective CABG between 2013 and 2018.
  • Left ventricular mass index calculated using the Devereux formula, categorizing patients into normal and increased groups.
  • Evaluation of mortality rates, postoperative complications (including atrial fibrillation and renal function), and echocardiographic parameters.

Main Results:

  • Patients with increased left ventricular mass had significantly higher 5-year mortality rates (27.2% vs. 11.5%, p < 0.001).
  • Higher incidence of postoperative atrial fibrillation (24.8% vs. 16.0%) and carotid stenosis (21.8% vs. 12.5%) observed in the increased mass group.
  • Elevated preoperative creatinine and C-reactive protein, with impaired postoperative kidney function, were noted in patients with increased left ventricular mass.

Conclusions:

  • Left ventricular mass and geometry are independent predictors of long-term prognosis in CABG patients.
  • Mitigating left ventricular remodeling may improve postoperative outcomes and long-term survival.
  • Further research into therapeutic interventions for adverse left ventricular changes is warranted.
Abstract

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