Task-induced ST segment depression, ectopic beats, and autonomic responses in coronary heart disease patients
Abstract:
The relationship between psychologically induced autonomic responses, ST segment depression, and ectopy was examined in patients with coronary artery disease (CAD) and controls. Both groups underwent a battery of performance tasks and interviews. Performance tasks were selected to yield predictable sympathetic and vagal responses. Autonomic activation in response to stimuli was documented using heart rate, blood pressure, and vascular indices. ST segment depression was observed in a significant portion of the sample. In subjects with CAD, ST segment depression, but not ectopy, was specifically associated with mental arithmetic. In this task, autonomic changes occurred, suggesting beta sympathetic activation. The prevalence of ST segment depression during mental arithmetic declined when a task-inducing brief, phasic vagal activation was combined with the mental arithmetic. Ectopic beats were not associated with a specific task among either patients or controls. The results supported the importance of psychologically induced autonomic response for the precipitation and inhibition of ST segment depression in patients with CAD.
More Related Videos
06:39Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Related Concept Videos
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Dysrhythmias V: Evaluating Dysrhythmias
Cardiomyopathy III: Hypertrophic Cardiomyopathy
