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Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
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Association between chronic pain and substance use.

Rezaul Karim Ripon1, Nasim Maleki2,3

  • 1Harvard T H Chan School of Public Health, Boston, USA.

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Chronic pain significantly increases the risk of substance use, especially polysubstance use. Addressing chronic pain may help reduce substance use risks.

Keywords:
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Area of Science:

  • Public Health
  • Epidemiology
  • Pain Management

Background:

  • Chronic pain affects millions globally, often leading to detrimental coping mechanisms like substance use.
  • Understanding the link between chronic pain and substance use is crucial for public health.
  • Previous research indicates a potential association, but further investigation is warranted.

Purpose of the Study:

  • To examine the relationship between chronic pain and substance use.
  • To compare the odds of substance use among individuals with and without chronic pain.
  • To identify specific risks associated with single and polysubstance use in relation to chronic pain.

Main Methods:

  • Case-control study utilizing data from the National Health and Nutrition Examination Study (NHANES).
  • Descriptive analysis and logistic regression models were employed.
  • Analysis included 980 individuals, categorizing them by substance use status and pain history (ongoing or chronic).

Main Results:

  • Polysubstance users exhibited a significantly higher risk of current or past chronic pain (aORs 2.28-6.30).
  • Single substance users also showed an increased risk of chronic pain (aORs 1.19-2.14).
  • Higher prevalence of ongoing pain was observed in single (23.36%) and polysubstance users (39.21%) compared to non-users (19.33%).

Conclusions:

  • Chronic pain is strongly associated with an elevated risk of substance use, particularly polysubstance use.
  • Findings underscore the need for integrated treatment approaches for chronic pain and substance use disorders.
  • Targeted interventions for chronic pain management may serve as a preventative strategy for substance use.