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Updated: Sep 17, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
Comparing warming strategies to reduce hypothermia and shivering in elderly abdominal or pelvic surgery patients: a
Wenyun Zheng1, Bin Huang2, Li Bao3
1Department of Nursing, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, China. 2614292@zju.edu.cn.
Abstract:
Perioperative hypothermia (PHT) and shivering represent significant clinical challenges in geriatric surgical populations. This network meta-analysis (NMA) systematically evaluates the comparative efficacy of various warming interventions in preventing PHT and shivering among elderly patients undergoing abdominal or pelvic surgery. We conducted a comprehensive literature search across PubMed, EMBASE, Cochrane library, and China Wanfang databases for randomized controlled trials (RCTs) published up to April 2024. Inclusion criteria encompassed RCTs comparing warming strategies in patients aged ≥ 60 years undergoing abdominal or pelvic surgery. Methodological quality was assessed using the Cochrane Risk of Bias tool 2.0. Primary outcomes included incidence rates of PHT and shivering. A frequentist approach to NMA was performed using random-effects models, with surface under the cumulative ranking curve (SUCRA) values calculated for treatment ranking. The analysis incorporated 18 RCTs (n = 2161) evaluating eight distinct warming strategies. Network meta-analysis revealed that forced-air warming with blankets at ≥ 40 °C (FABWH) demonstrated superior efficacy for PHT prevention, while forced-air warming at ≥ 40 °C (FAWH) showed optimal performance for shivering reduction. Compared to standard care, FABWH significantly reduced PHT risk (RR = 0.14, 95% CI 0.04-0.46; P = 0.0012) and shivering incidence (RR = 0.21, 95% CI 0.07-0.69; P = 0.008). FAWH exhibited comparable effectiveness, with risk reductions of 72% for PHT (RR = 0.28, 95% CI 0.13-0.58; P = 0.0006) and 84% for shivering (RR = 0.16, 95% CI 0.07-0.39; P < 0.001). This NMA provides robust evidence that active warming strategies, particularly FABWH and FAWH, significantly mitigate PHT and shivering risks in elderly surgical patients. Future research should focus on long-term outcomes and cost-effectiveness analyses to optimize clinical decision-making.
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